Coenzyme Q10: The revolutionary powerful anti-aging antioxidant

Coenzyme Q10: The revolutionary powerful anti-aging antioxidant

Longévité, Molécules et longévité, Suppléments naturels personnalisés -

Introduction to Coenzyme Q10: A Key Antioxidant for Longevity

Coenzyme Q10, also known as ubiquinone, is a powerful antioxidant and an essential element of natural supplements dedicated to anti-aging. This vital compound plays a crucial role in supporting longevity by actively participating in the energy metabolism of our cells and fighting the signs of aging.

Today, its anti-oxidant effect is the subject of many studies aimed at reducing the effects of aging on our skin, our heart or our brain. At the same time, it has been demonstrated that coenzyme Q10, naturally present in our cells, is a good biomarker of biological age: its plasma concentration decreases over time but also during pathological processes such as cancer, neurodegenerative diseases, diabetes or cardiovascular disease

The Antioxidant Role of Coenzyme Q10 in Longevity

The vitamin structure of Coenzyme Q10 allows it to actively participate in the transport of electrons in the mitochondria, thus guaranteeing optimal production of ATP, our endogenous energy source. As an antioxidant, it protects our cells and lipoproteins against oxidation, playing a preventive role against cardiovascular diseases and cellular aging.

Cardiovascular and Antioxidant Protection

Coenzyme Q10, thanks to its antioxidant properties, offers significant protection against cardiovascular diseases, a key factor for increased longevity. It prevents the oxidation of blood lipids, thereby reducing the risk of developing heart diseases.

Neuroprotection and Reduction of Oxidative Stress

As an antioxidant, Coenzyme Q10 plays an essential role in neuronal protection, contributing to the prevention of neurodegenerative diseases. This neuroprotective action is crucial for maintaining optimal cognitive function, a vital aspect of anti-aging.

Fights Cellular Aging

The antioxidant action of Coenzyme Q10 protects cells against oxidative damage, thus delaying the cellular aging process. This protection is fundamental to promoting cellular longevity and healthy aging.

Mitochondrial and Energy Support

Coenzyme Q10 improves mitochondrial function through its antioxidant properties, optimizing energy production and combating age-related energy decline. This energetic support is essential for a long and active life.



Coenzyme Q10 is recognized for its high safety profile. However, it is recommended to source supplements from reliable manufacturers to ensure product purity. Mild gastrointestinal upset may occur with high doses.

Coenzyme Q10 is widely studied and has not shown toxicity in humans when taken in commonly recommended dosages. Its use is considered safe for the majority of adults.


Coenzyme Q10 is an essential natural antioxidant supplement for anyone looking to support longevity and combat the signs of aging. Its ability to protect against cardiovascular disease, provide neuroprotective protection, fight cellular aging, and support mitochondrial function makes it a pillar of health and well-being at all ages.


Garrido-Maraver J. et al., Clinical applications of coenzyme Q10. Front Biosci (Landmark Ed), 2014 Jan 1;19:619-33

Crane FL. Biochemical functions of coenzyme Q10. J Am Coll Nutr. 2001;20:591–598

Groneberg DA, Kindermann B, Althammer M, Klapper M, Vormann J, et al. Coenzyme Q10 affects expression of genes involved in cell signaling, metabolism and transport in human CaCo-2 cells. Int J Biochem Cell Biol. 2005;37:1208–1218

Schmelzer C, Lindner I, Rimbach G, Niklowitz P, Menke T, Döring F. Functions of coenzyme Q10 in inflammation and gene expression. Biofactors. 2008;32:179–183

Santos-González M, Gómez Díaz C, Navas P, Villalba JM. Modifications of plasma proteome in long-lived rats fed on a coenzyme Q10-supplemented diet. Exp Gerontol. 2007;42:798–806

Witting PK, Pettersson K, Letters J, Stocker R. Anti-atherogenic effect of coenzyme Q10 in apolipoprotein E gene knockout mice. Free Radic Biol Med, 2000, 29(3–4):295–305

Tsai KL, Chen LH et al., Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway. Mol Nutr Food Res, 2011, 55(Suppl 2):S227–S240

Stoyanovsky DA, Osipov AN, Quinn PJ, Kagan VE. Ubiquinone-dependent recycling of vitamin E radicals by superoxide. Arch Biochem Biophys. 1995 Nov 10; 323(2):343-51

Hernandez-Ojeda J, Cardona-Munoz EG et al., The effect of ubiquinone in diabetic polyneuropathy: a randomized double-blind placebo-controlled study. J Diabetes Complicatet, 2012, 26(4):352–358

Shults CW, Flint Beal M, Song D, Fontaine D. Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease. Exp Neurol. 2004;188:491–494

Lee J, Boo JH, Ryu H. The failure of mitochondria leads to neurodegeneration: do mitochondria need a jump start? Adv Drug Deliv Rev. 2009;61:1316–1323

Rusciani L, Proietti I, Rusciani A, Paradisi A, Sbordoni G, et al. Low plasma coenzyme Q10 levels as an independent prognostic factor for melanoma progression. J Am Acad Dermatol. 2006;54:234–241

Ben-Meir A, Burstein E, Borrego-Alvarez A, et al. Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging. Aging Cell. 2015;14(5):887-895

Knott A, Achterberg V, Smuda C, et al. Topical treatment with coenzyme Q10‐containing formulas improves skin's Q10 level and provides antioxidative effects. Biofactors (Oxford, England). 2015;41(6):383-390

Yadav NK, Nanda S, Sharma G, Katare OP. Systematically optimized coenzyme q10-loaded novel proniosomal formulation for treatment of photo-induced aging in mice: characterization, biocompatibility studies, biochemical estimations and anti-aging evaluation. J Drug Target. 2016;24(3):257-71