Olive Leaves: A Treasure of Polyphenols for Longevity




Olive Leaves: A Treasure of Polyphenols for Longevity

Longévité, Molécules et longévité, Suppléments naturels personnalisés -

Olive Leaves: An Elixir of Youth Hidden in the Mediterranean

At the heart of the Mediterranean diet, recognized worldwide for its benefits on health and longevity, is a less talked about but equally powerful ingredient: olive leaves. These leaves, which envelop the precious olives, are a rich source of polyphenols, phytochemical compounds that offer remarkable protection against disease and aging. Among these polyphenols, oleuropein stands out for its anti-inflammatory and antioxidant effects, making olive leaves a key component of natural supplements intended to improve longevity and combat anti-aging. In this article, we delve into the secrets of these green leaves and reveal how they can transform your health and well-being.

Oleuropein: The Key Polyphenol of Olive Leaves

Oleuropein, the primary polyphenol found in olive leaves, is known for its exceptional anti-inflammatory and antioxidant properties. Able to reduce bad cholesterol, blood pressure, and protect against oxidative damage, oleuropein plays a crucial role in preventing cancer and slowing cognitive decline. Its ability to regenerate cells and fight tumors illustrates its remarkable potential in promoting longevity and anti-aging.

Cardiovascular and Metabolic Benefits

Olive leaf extracts, thanks to their richness in oleuropein, have demonstrated significant effects in reducing blood pressure and improving cardiovascular health. By acting as a natural vasodilator, these extracts promote better blood circulation and reduce the risk of heart disease. In addition, their beneficial action on blood sugar regulation makes them an ideal supplement for the prevention and management of diabetes.

Protection against Neurodegenerative Diseases

The anti-inflammatory and antioxidant properties of olive leaves also contribute to neuronal protection, providing a barrier against neurodegenerative diseases such as Alzheimer's and Parkinson's. By inhibiting oxidation and reducing inflammation, olive leaf polyphenols help maintain brain cell integrity and preserve cognitive function.

SIDE EFFECTS

LITTLE TOXIC EFFECTS

Olive leaf extracts are well tolerated by the majority of people. However, it is essential to opt for supplements from reliable sources. Minor side effects may include gastrointestinal reactions in some users.

Active compounds in olive leaves, notably oleuropein, have not demonstrated toxicity in humans, highlighting their safety for regular use as part of controlled supplementation.

Conclusion

Olive leaves and their rich polyphenol content, particularly oleuropein, prove to be valuable allies in combating inflammation, promoting longevity, and preventing anti-aging. By integrating these natural supplements into our daily regimen, we can benefit from their vast health benefits, supporting our quest for a longer, healthier life.

SOURCES:

Omar SH. Oleuropein in olive and its pharmacological effects. Sci Pharm. 2010;78(2):133-54.

Wahle KW, Caruso D, Ochoa JJ, Quiles JL. Olive oil and modulation of cell signaling in disease prevention. Lipids.2004 Dec;39(12):1223-31.

Hamdi HK, Castellon R. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem Biophys Res Commun.2005 Sep 2;334(3):769-78.

Somova LI, Shode FO, Ramnanan P, Nadar A. Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves. J Ethnopharmacol.2003 Feb;84(2-3):299-305.

Khayyal MT, el-Ghazaly MA, Abdallah DM, Nassar NN, Okpanyi SN, Kreuter MH. Blood pressure lowering effect of an olive leaf extract (Olea europaea) in L-NAME induced hypertension in rats. Arzneimittelforschung.2002;52(11):797-802.

Cherif S, Rahal N, Haouala M, et al. A clinical trial of a titrated Olea extract in the treatment of essential arterial hypertension. J Pharm Belg. 1996 Mar-Apr;51(2):69-71.

Susalit E, Agus N, Effendi I, et al. Olive (Olea europaea) leaf extract effective in patients with stage-1 hypertension: comparison with Captopril. Phytomedicine.2011 Feb 15;18(4):251-8.

Scheffler A, Rauwald HW, Kampa B, Mann U, Mohr FW, Dhein S. Olea europaea leaf extract exerts L-type Ca(2+) channel antagonistic effects. J Ethnopharmacol.2008 Nov 20;120(2):233-40.

Scoditti E, Calabriso N, Massaro M, et al. Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: A potentially protective mechanism in atherosclerotic vascular disease and cancer. Arch Biochem Biophys. 2012 Nov 15;527(2):81-9.

Jemai H, Bouaziz M, Fki I, El Feki A, Sayadi S. Hypolipidimic and antioxidant activities of oleuropein and its hydrolysis derivative-rich extracts from Chemlali olive leaves. Chem Biol Interact. 2008 Nov 25;176(2-3):88-98.

Visioli F, Galli C. Oleuropein protects low density lipoprotein from oxidation. Life Sci. 1994;55(24):1965-71.

Wang L, Geng C, Jiang L, et al. The anti-atherosclerotic effect of olive leaf extract is related to suppressed inflammatory response in rabbits with experimental atherosclerosis. Eur J Nutr. 2008 Aug;47(5):235-43.

Carluccio MA, Siculella L, Ancora MA, et al. Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals. Arterioscler Thromb Vasc Biol. 2003 Apr 1;23(4):622-9.

Turner R, Etienne N, Alonso MG, et al. Antioxidant and anti-atherogenic activities of olive oil phenolics. Int J Vitam Nutr Res. 2005 Jan;75(1):61-70.

Singh I, Mok M, Christensen AM, Turner AH, Hawley JA. The effects of polyphenols in olive leaves on platelet function. Nutr Metab Cardiovasc Dis. 2008 Feb;18(2):127-32.

Gonzalez M, Zarzuelo A, Gamez MJ, Utrilla MP, Jimenez J, Osuna I. Hypoglycemic activity of olive leaf. Planta Med. 1992 Dec;58(6):513-5.

Anter J, Fernandez-Bedmar Z, Villatoro-Pulido M, et al. A pilot study on the DNA-protective, cytotoxic, and apoptosis-inducing properties of olive-leaf extracts. Mutat Res. 2011 Aug 16;723(2):165-70.

Corona G, Deiana M, Incani A, Vauzour D, Dessi MA, Spencer JP. Inhibition of p38/CREB phosphorylation and COX-2 expression by olive oil polyphenols underlies their anti-proliferative effects. Biochem Biophys Res Commun. 2007 Oct 26;362(3):606-11.