Curcumin from Turmeric: A Natural Supplement Against Inflammation and Aging

Curcumin from Turmeric: A Natural Supplement Against Inflammation and Aging

Longévité, Molécules et longévité, Suppléments naturels personnalisés -

Turmeric: A Valuable Ally Against Inflammation and Aging

Curcumin, the active component of turmeric, is recognized for its exceptional properties in the fight against inflammation and aging. Used for centuries in Indian cuisine and traditional Chinese medicine, this molecule offers a wide range of health benefits, affirming its place among essential natural supplements for longevity and anti-aging.

Anti-inflammatory and Antioxidant Properties

Curcumin stands out for its powerful anti-inflammatory and antioxidant effect, playing a crucial role in the prevention and treatment of metabolic, neurodegenerative diseases, and certain types of cancer. These diseases share a common phenomenon: inflammation. By modulating pro-inflammatory molecules and enzymes, curcumin contributes to a healthier body environment that is resilient to disease.

Impact on Cellular Aging

Beyond its effects on inflammation, curcumin positively influences the overall aging of our body. It intervenes in gene regulation, in particular by attaching to genes coding for certain pro-cancer proteins, thus reducing the size of tumors and increasing the survival rate. Furthermore, its action on telomerase, the enzyme responsible for telomere elongation, suggests remarkable potential for extending cellular lifespan and, by extension, longevity.

Various and Beneficial Uses of Curcumin

Curcumin finds use in an impressive variety of applications, from preventing skin aging to combating autoimmune diseases, thanks to its anti-inflammatory and antioxidant properties. It also promotes neurogenesis, which is particularly promising for the treatment of memory disorders and the prevention of neurodegenerative diseases.

Prevention of Skin Aging

When applied topically, curcumin visibly reduces wrinkles and sebum production, while providing systemic antioxidant protection against skin aging.

Increased Neurogenesis

Animal studies have shown that curcumin stimulates the formation of new neurons, particularly in the hippocampus, a significant advance for memory and cognitive function.

Treatment of Autoimmune Diseases

Curcumin supplementation is recommended for its beneficial action in the treatment of autoimmune conditions, such as lupus, thanks to its powerful anti-inflammatory effect.



Although turmeric and its active component curcumin are generally well tolerated, choosing high-quality supplements is essential. At high doses, some individuals may experience digestive discomfort.

Curcumin, known for its beneficial effects on health, does not present notable toxicity in humans when consumed in recommended quantities, affirming its safety of use.


Turmeric's curcumin presents itself as a must-have natural supplement for those looking to combat inflammation and promote longevity and anti-aging. With its wide applications and proven benefits, it embodies a natural and powerful solution for maintaining optimal health and slowing the effects of time.


Venigalla M, Gyengesi E, Munch G. Curcumin and Apigenin – novel and promising therapeutics against chronic neuroinflammation in Alzheimer's disease. Neural Regen Res. 2015;10(8):1181-5

Goel A, Aggarwal BB. Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs. Nutr Cancer. 2010;62(7):919-30

Cheng CY, Lin YH, Su CC. Curcumin inhibits the proliferation of human hepatocellular carcinoma J5 cells by inducing endoplasmic reticulum stress and mitochondrial dysfunction. Int J Mol Med. 2010;26(5):673-8

Chen Q, Gao Q, Chen K, et al. Curcumin suppresses migration and invasion of human endometrial carcinoma cells. Oncol Lett. 2015;10(3):1297-302

Cole GM, Teter B, Frautschy SA. Neuroprotective effects of curcumin. Adv Exp Med Biol. 2007;595:197-212

Sikora E, Bielak-Zmijewska A, Mosieniak G, Piwocka K. The promise of slow down aging may come from curcumin. Curr Pharm Des. 2010;16(7):884-92

Bose S, Panda AK, Mukherjee S, et al. Curcumin and tumor immune-editing: resurrecting the immune system. Cell Div. 2015;10:6

Xiao Z, Zhang A, Lin J, et al. Telomerase: a target for therapeutic effects of curcumin and a curcumin derivative in aβ1-42 insult in vitro. PLoS One. 2014 Jul 1;9(7):e101251

Vaughn AR, Branum A, Sivamani RK. Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytother Res. 2016 Aug;30(8):1243-64

Jurenka JS. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. Altern Med Rev. 2009 Jun;14(2):141-53

Kim SJ, Son TG, Park HR, et al. Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus. J Biol Chem. 2008;283(21):14497-505

Kang SK, Cha SH, Jeon HG. Curcumin-induced histone hypoacetylation enhances caspase-3-dependent glioma cell death and neurogenesis of neural progenitor cells. Stem Cells Dev. 2006;15(2):165-74

Zaahkouk AM, Abdel Aziz MT et al. Efficacy of a novel water-soluble curcumin derivative versus sildenafil citrate in mediating erectile function. Int J Tax Res. 2015 Jan-Feb;27(1):9-15

Soni KB, Kuttan R. Effect of oral curcumin administration on serum peroxides and cholesterol levels in human volunteers. Indian J Physiol Pharmacol. 1992;36(4):273-5

Chainani-Wu N. Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). J Altern Complement Med. 2003 Feb;9(1):161-8